cAMP Hunter™ Tirzepatide (GIP RA) Bioassay Kit

Background Information:

The cAMP Hunter™ Tirzepatide (GIP RA) Bioassay Kit has been qualified with Tirzepatide. This bioassay provides a robust, and highly sensitive functional, cell-based assay to monitor 3’-5’-cyclic adenosine monophosphate (cAMP) production in cells, as a result of Tirzepatide mediated activation of GIP receptor. The bioassay kit contains all the materials needed for a complete assay, including cells, detection reagents, cell plating reagent, positive control agonist, and assay plates. The ready-to-use cryopreserved cells have been manufactured to ensure assay reproducibility and faster implementation from characterization to QC lot-release. This bioassay has been optimized for a 96-well format. Note that control agonist for stimulating the cells, GIP (Gastric Inhibitory Peptide), may not be included in the kit, and may be purchased separately.

Please reach out to Tech Support at DiscoverXSupportUS@discovery.eurofinsus.com for lot specific CoA.

Target Class:

GPCR

Family:

Glucagon

Sub Family:

Class B

Protein Name:

GIPR

Protein Aliases:

Glucose-dependent insulinotropic polypeptide receptor

Accession Number:

NM_000164

UniProt Number:

P48546

Gene Name:

GIPR

Gene ID:

2696

Target Species:

Human

Cell Background:

CHO-K1