Biological Information

Background Information:

The PathHunter® IL-2 Bioassay Kit (Dimerization) is a functional, robust, highly sensitive, and easy-to-use-cell based assay to study drug potency and neutralizing antibodies. This bioassay enables quantitation of IL-2 mediated Dimerization of the IL-2 receptor. Each PathHunter IL-2 bioassay kit contains all the materials needed to perform a complete assay, including cryopreserved, single-use cells, detection reagents, cell plating reagent, agonist for stimulating the cells, and assay plates. This bioassay has been optimized for a 96-well plate format.

Target Class:

Cytokine Receptor

Family:

IL-2 Receptor

Protein Name:

IL2RB

Protein Aliases:

IL-2R subunit beta|IL-2RB|High affinity IL-2 receptor subunit beta|Interleukin-15 receptor subunit beta|p70-75|p75|CD antigen CD122

Accession Number:

NM_000878.3

UniProt Number:

P14784

Gene Name:

IL2RB

Gene ID:

3560

Gene Aliases:

IL15RB

Target Species:

Human

Cell Background:

U2OS

Usage

Product Type:

Bioassay Kits

Application:

Potency, Commercial Release & Stability

Kit Components:

KitComponent

Storage Conditions:

Store in vapor phase of liquid nitrogen.

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Cell Based

Assay Measures:

Dimerization

Detection Method:

Chemiluminescence

Clinical Relevance

Therapeutic Area:

Inflammation/Allergy

Additional Information

Brand:

PathHunter®