Biological Information
Background Information:
The PathHunter® IL-2 Bioassay Kit (Dimerization) is a functional, robust, highly sensitive, and easy-to-use-cell based assay to study drug potency and neutralizing antibodies. This bioassay enables quantitation of IL-2 mediated Dimerization of the IL-2 receptor. Each PathHunter IL-2 bioassay kit contains all the materials needed to perform a complete assay, including cryopreserved, single-use cells, detection reagents, cell plating reagent, agonist for stimulating the cells, and assay plates. This bioassay has been optimized for a 96-well plate format.
Target Class:
Cytokine Receptor
Family:
IL-2 Receptor
Protein Name:
IL2RB
Protein Aliases:
IL-2R subunit beta|IL-2RB|High affinity IL-2 receptor subunit beta|Interleukin-15 receptor subunit beta|p70-75|p75|CD antigen CD122
Accession Number:
NM_000878.3
UniProt Number:
P14784
Gene Name:
IL2RB
Gene ID:
3560
Gene Aliases:
IL15RB
Target Species:
Human
Cell Background:
U2OS
Usage
Product Type:
Bioassay Kits
Application:
Potency, Commercial Release & Stability
Kit Components:
Storage Conditions:
Store in vapor phase of liquid nitrogen.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Cell Based
Assay Measures:
Dimerization
Detection Method:
Chemiluminescence
Clinical Relevance
Therapeutic Area:
Inflammation/Allergy
Additional Information
Brand:
PathHunter®