Consider Eurofins DiscoverX’s custom development capabilities for custom cell lines, assays, & enzyme development.
Cell banking plays a crucial role in supporting the development of therapeutics and involves the preservation and storage of cells, tissues, or cell lines that serve as repositories of valuable biological resources. Cell banks provide researchers with consistent and reliable cell populations for a myriad of applications from drug discovery to QC lot-release, including high-throughput screening, preclinical studies, lot release testing, and therapeutic manufacturing.
Complementing cell banking, Eurofins DiscoverX® offers custom scale-up cell production capabilities catering to the specialized needs of drug developers and biotechnology companies by facilitating the transition from laboratory-scale cell cultures to large-scale production. Through meticulous process optimizations and robust manufacturing, custom scale-up enables efficient and scalable production of cells for diverse applications.
Confidently de-risk your drug development programs by establishing dedicated cell banks with Eurofins DiscoverX.
Consider Eurofins DiscoverX’s custom development capabilities for custom cell lines, assays, & enzyme development.
Cell banking is an essential practice in biotechnology regenerative medicine and biomedical research that involves the preservation and storage of cells, tissues, or cell lines under controlled conditions for future use. Cell banking is a critical aspect for both therapeutic producer cell lines (called Producer Cell Bank) as well as cells used as analytical reagents (called Analytical Cell Bank). Generating an analytical cell bank ensures the availability of well-characterized and genetically stable cell populations for (1) discovery to preclinical studies, minimizing variability between experiments, ensuring the reliability and validity of experimental results, and (2) lot-release applications, such as potency testing, ensuring long-term assay reproducibility and supply assurance. Cell banking also plays a vital role in supporting regulatory compliance by providing documentation of cell line authentication, characterization, and handling procedures for the critical reagents used, thereby demonstrating the reproducibility and reliability of preclinical findings.
Eurofins DiscoverX offers cell banking as a 2-tiered cell bank, which refers to a structured approach that involves the creation and maintenance of two distinct levels of cell banks: the Master Cell Bank (MCB) and the Working Cell Bank (WCB).
Establishing a well-characterized cell bank follows a systematic approach from expansion of source clone cells to testing and cryopreservation under strict quality control measures. Eurofins DiscoverX manufactures cell banks based on your program requirements for size, tiers, testing (standard or compendial), application, etc.
Currently, Eurofins DiscoverX cell banking capabilities are available for mammalian cells and there is an option for off-site storage for WCB vials.