AAK1, active

10 µg of active AAK1. N-terminal 6His-tagged, recombinant fragment of human AAK1.

Catalog #: 16-043

$399.00$2,989.00


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Biological Information
Background Information:
AAK1 (AP2 Associated Kinase 1) belongs to the SNF1 subfamily of serine/threonine protein kinases. This kinase is detected in brain, heart and liver, and plays an important role in regulating the clathrin-mediated endocytosis of the rabies virus, facilitating infection. Inhibitors of AAK1 are being studied as candidate therapeutics to disrupt the entry of viruses, including SARS-CoV-2, into target cells. It is also involved in positive regulation of Notch pathway signaling in mammals. [provided by RefSeq, Aug 2020]
Target Class:
Kinase
Accession Number:
NM_080836.2
Target Name:
AAK1
Target Aliases:
AP2 Associated Kinase 1, KIAA1048, AP2-Associated Protein Kinase, Adaptor-Associated Kinase 1
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
Usage Disclaimer:
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Datasheets

16-043x Datasheet

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