Alk, active

N-terminal 6His-tagged recombinant, human ALK, amino acids 1058-end.

Catalog #: 14-555

$399.00$2,989.00


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Biological Information
Background Information:
ALK or anaplastic lymphoma kinase (Ki-1) is a membrane-spanning tyrosine kinase receptor that is most closely related to leukocyte tyrosine kinase. No function has been ascribed for ALK; however, its restricted expression in neural tissue suggests that this receptor might play an important role in the normal development and function of the nervous system. Large-cell anaplastic lymphoma is a subtype of non-Hodgkin's lymphoma. Over half of these lymphomas have a chromosomal translocation t(2;5), that leads to the expression of a hybrid protein comprised of the nucleolar phosphoprotein nucleophosmin (NPM) and ALK. GenBank U62540
Target Class:
Kinase
Family:
Receptor Tyrosine Kinase (RTK): Type XIX RTK: Leukocyte tyrosine kinase (LTK) Receptor family
Accession Number:
NM_004304.3
Target Name:
ALK
Target Aliases:
ALK, CD246, TFG/ALK
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
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Datasheets

14-555x Datasheet

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