ARK5, active

N-terminal 6His-tagged recombinant, human ARK5 amino acids 2-end.

Catalog #: 14-661

$399.00$2,989.00


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Biological Information
Background Information:
ARK5 (AMPK related kinase 5) is a serine/threonine kinase and a member of the AMPK family of protein kinases. In response to stimulation by Akt, ARK5 prevents cell death induced by glucose starvation and death receptor activation in tumor cells as a result of inhibition of caspase 8 activation via preservation of c-FLIP. ARK5 can also negatively regulate procaspase-6 via direct phosphorylation at Ser257, leading to resistance to the FasL/Fas signaling system. GenBank NM_014840
Target Class:
Kinase
Accession Number:
NM_014840.2
Target Name:
NuaK1 (ARK5)
Target Aliases:
NUAK1, KIAA0537, ARK5, NuaK1
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
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Datasheets

14-661x Datasheet

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