Axl, active

N-terminal 6His-tagged recombinant, human Axl amino acids 473-end.

Catalog #: 14-512

$399.00$2,989.00


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Biological Information
Background Information:
AXL is a member of AXL protein-tyrosine kinase family and expressed human myeloid leukemia cells. Gas6, the protein product of the growth arrest-specific gene 6 (gas6), a member of the vitamin K-dependent protein family, was identified as a ligand for the Axl/Sky family of receptor tyrosine kinases. Gas6/Axl signaling has been related to the cell growth and protection from apoptosis in normal and cancer cells. GenBank NM_021913. The recombinant protein also contains the conflict Q764R with respect to GenBank NM_021913. This substitution is reported in GenBank BC032229. The residue coordinates in the native sequence are given.
Target Class:
Kinase
Family:
Receptor Tyrosine Kinase (RTK): Type XI RTK: TAM Receptor Family
Accession Number:
NM_001699.3; NM_021913.2
Target Name:
Axl
Target Aliases:
AXL receptor tyrosine kinase
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
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Datasheets

14-512x Datasheet

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