Biological Information | |
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Background Information: | Cyclin-dependent Kinase 7 (cdk7) is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
GenBank X79193 / GenBank U11791 / GenBank X87843 |
Target Class: | Kinase |
Family: | Serine/Threonine Kinase: CDK7 subfamily |
Accession Number: | NM_001799.2 |
Target Name: | CDK7/cyclinH/MAT1 |
Target Aliases: | CDK7, p39MO15, CAK, CAK1, MO15, CDKN7, STK1 |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 1 year at -70°C |
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Cdk7/Cyclin H/MAT1 (CAK complex), active
Datasheets
14-476x Datasheet
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