EphA5, active

N-terminal 6His-tagged recombinant, human EphA5 amino acids 655-956.

Catalog #: 14-639

$399.00$2,989.00


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Biological Information
Background Information:
Eph (erythropoietin-producing hepatocellular) family tyrosine kinase receptors consist of two groups: EphA group members respond to ephrin-A, which is anchored to the cell membrane by glycosylphosphatidylinositol, whereas EphB group members respond to ephrin-B, containing a transmembrane domain. Among them, only EphA4 can cross-respond to both ephrin-A and -B. EphA5 (EHK1, HEK7, CEK7, TYRO4) is widely distributed in CNS. The localization of EphA5 to motor and sensory neurons is consistent with a role of EphA5 in neural plasticity, cell-cell recognition, and topographical orientation of neuronal systems. GenBank NM_004439
Target Class:
Kinase
Family:
Receptor Typosine Kinase (RTK): Growth Factor Receptor
Accession Number:
NM_004439.4; NM_182472.1
Target Name:
EphA5
Target Aliases:
EPHA5, EphA5, EHK1, TYRO4, HEK7, CEK7, Hek7
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
Usage Disclaimer:
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Datasheets

14-639x Datasheet

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