Hck, activated

N-terminal 6His-tagged recombinant, human Hck amino acids 230–497 .

Catalog #: 14-843

$399.00$2,989.00


Inquire
Biological Information
Background Information:
Hematopoietic cell kinase (HCK) is a member of Src protein-tyrosine kinase family and expressed primary in granulocytes, monocytes and macrophages. Active HCK phosphorylates STAT5B on Tyr699, which represents an essential step in Signal transducer and activator of transcription 5 (STAT5B) stimulation. The binding of SH3 ligands, such as the Nef protein of HIV-1, further augments Hck activity suggesting a new mechanism for regulating tyrosine kinase activity. GenBank NM_002110
Target Class:
Kinase
Family:
Cytosolic Tyrosine Kinase
Accession Number:
NM_002110.2
Target Name:
Hck
Target Aliases:
HCK, p59-HCK/p60-HCK, JTK9
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
Usage Disclaimer:
These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Datasheets

14-843x Datasheet

View Document