Biological Information | |
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Background Information: | MAP4K3 is a member of the mitogen-activated protein Kinase kinase family. The encoded protein activates key effectors in cell Signaling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. Among its related pathways are TGF-Beta Pathway and Angiopoietin-like protein 8 regulatory pathway. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is MAP4K5.[provided by RefSeq, Jul 2012] |
Target Class: | Kinase |
Family: | Ser/Thr Kinase |
Accession Number: | GenBank NM_003618.2 |
Target Name: | MAP4K3 |
Target Aliases: | Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3, Germinal Center Kinase-Related Protein Kinase, MAPK/ERK Kinase Kinase Kinase 3, MEK Kinase Kinase 3, Germinal Center Kinase-Like Kinase |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 1 year at -70°C |
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MAP4K3, active
active MAP4K3. N-terminal GST-tagged and C-terminal 6His tagged, recombinant, human MAP4K3 amino acids 1-291.
Datasheets
15-030x Datasheet
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