MEK2, active

N-terminal 6His-tagged recombinant, human full length MEK2.

Catalog #: 14-528

$399.00$2,989.00


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Biological Information
Background Information:
MEK2 protein is a dual specificity protein kinase that belongs to the MAP Kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP Kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax. It catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity). GenBank NM_030662
Target Class:
Kinase
Family:
Ser/Thr Kinase
Accession Number:
NM_030662
Target Name:
MEK2
Target Aliases:
MAP2K2, PRKMK2, ERK Activator Kinase 2, MAP Kinase Kinase 2, MAPK/ERK Kinase 2
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
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Datasheets

14-528x Datasheet

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