MLK3, active

Active MLK3. N-terminal GST-tagged, recombinant, human MLK3 amino acids 1-468.

Catalog #: 16-039

$399.00$2,989.00


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Biological Information
Background Information:
MLK3 is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008]
Target Class:
Kinase
Accession Number:
GenBank NM_002419.2
Target Name:
MLK3
Target Aliases:
Mitogen-Activated Protein Kinase Kinase Kinase 11, MEKK11, Src-Homology 3 Domain-Containing Proline-Rich Kinase, Mixed Lineage Kinase 3, SH3 Domain-Containing Proline-Rich Kinase, Protein-Tyrosine Kinase PTK1, EC 2.7.11
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
Usage Disclaimer:
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Datasheets

16-039x Datasheet

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