MuSK, active

N-terminal 6His-tagged recombinant, human MuSK amino acids 530-end.

Catalog #: 14-634

$399.00$2,989.00


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Biological Information
Background Information:
MuSK (Muscle Associated Receptor Tyrosine Kinase) is a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane. [provided by RefSeq, Oct 2009]
Target Class:
Kinase
Accession Number:
NM_005592.1
Target Name:
MuSK
Target Aliases:
MUSK, MuSK, MGC126323, MGC126324
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
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Datasheets

14-634x Datasheet

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