NEK3, active

N-terminal 6His-tagged recombinant, human full length NEK3.

Catalog #: 14-694

$399.00$2,989.00


Inquire
Biological Information
Background Information:
NEK3 (NIMA-related kinase 3) is a serine/threonine protein kinase that belongs to the NIMA (Never in Mitosis A)-related kinase family. It is involved in a variety of cellular processes, including cell cycle regulation, mitosis, apoptosis, and cytoskeletal organization. NEK3 has a conserved kinase domain, a C-terminal regulatory domain, and a nuclear localization signal. It is expressed in a wide range of tissues and cell types and is regulated by various post-translational modifications, including phosphorylation, acetylation, and ubiquitination. Recent studies have suggested that NEK3 plays a critical role in promoting tumor growth and survival, making it a potential target for cancer therapy. Additionally, NEK3 has been implicated in a number of other diseases, including heart disease and Alzheimer's disease.
Target Class:
Kinase
Accession Number:
NM_002498.2; NM_152720.1
Target Name:
NEK3
Target Aliases:
NEK3, HSPK36, MGC29949
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
Usage Disclaimer:
These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Datasheets

14-694x Datasheet

View Document