SGK1 (delta1-59, S422D), active

N-truncated (missing N-terminal 60 amino acids), 6His-tagged recombinant, human SGK1 fusion protein, containing a S422D mutation.

Catalog #: 14-331

$399.00$2,989.00


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Biological Information
Background Information:
The serum/glucocorticoid regulated kinases (SGK1,2,3) are serine/threonine kinases that belong to the AGC (protein kinase A; protein kinase G and protein kinase C) subfamily that includes cAMP and cGMP dependent kinases, PKB and PKC. SGK1 (SGK) is predominately expressed in kidney, liver and pancreas. The catalytic domain of serum/glucocorticoid regulated protein kinase is most similar to PKB and activated via phosphorylation mechanism when cells are stimulated with insulin, IGF1 or serum, or exposed to oxidative stress. GenBank AF153609. The protein is S422D with respect to this accession number.
Target Class:
Kinase
Accession Number:
NM_005627.2
Target Name:
SGK1
Target Aliases:
SGK, SGK1
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
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Datasheets

14-331x Datasheet

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