SRPK2, active

N-terminal GST-tagged recombinant, human SRPK2 amino acids 46-end.

Catalog #: 14-666

$399.00$2,989.00


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Biological Information
Background Information:
Two SR Protein-specific Kinases, SRPK1 and SRPK2, have been shown to phosphorylate specifically the RS motifs of the SR family of splicing factors. Phosphorylation of an SR protein (ASF/SF2) by either SRPK1 or 2 enhanced its interaction with another RS domain-containing protein, and overexpression of either kinase induced specific redistribution of splicing factors in the nucleus. SRPK2 contains a proline-rich sequence at its NH2 terminus, the capacity to interact with a WW domain protein in vitro. Inhibition of SRPK2 may render male germ cell and other tumors insensitive to cisplatin. GenBank NM_182691
Target Class:
Kinase
Accession Number:
NM_182691.1; NM_182692.1
Target Name:
SRPK2
Target Aliases:
SRPK2, FLJ36101, WUGSC:H_RG152G17.1a, SFRSK2, H_RG152G17.1b, H_RG152G17.1a
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
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Datasheets

14-666x Datasheet

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