Tec, activated

N-terminal 6His-tagged recombinant, human Tec amino acids 174-end. Autoactivated by incubating with Mg/ATP, excess ATP and MgAc removed by gel filtration.

Catalog #: 14-801

$399.00$2,989.00


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Biological Information
Background Information:
TEC is involved in G protein-coupled receptor- and integrin-mediated signalings in blood platelets. It plays a role in hepatocyte proliferation and liver regeneration and is involved in HGF-induced ERK signaling pathway. TEC regulates also FGF2 unconventional secretion (endoplasmic reticulum (ER)/Golgi-independent mechanism) under various physiological conditions through phosphorylation of FGF2 'Tyr-215'. May also be involved in the regulation of osteoclast differentiation. GenBank NM_003215. The recombinant protein contains the amino acid substitution F514V with reference to NM_003215. F514V is reported in GenBank CB985022.
Target Class:
Kinase
Accession Number:
Refer to CoA for Accession Number
Target Name:
Tec
Target Aliases:
TEC, PSCTK4
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
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Datasheets

14-801x Datasheet

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