Biological Information | |
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Background Information: | TEC is involved in G protein-coupled receptor- and integrin-mediated signalings in blood platelets. It plays a role in hepatocyte proliferation and liver regeneration and is involved in HGF-induced ERK signaling pathway. TEC regulates also FGF2 unconventional secretion (endoplasmic reticulum (ER)/Golgi-independent mechanism) under various physiological conditions through phosphorylation of FGF2 'Tyr-215'. May also be involved in the regulation of osteoclast differentiation.
GenBank NM_003215. The recombinant protein contains the amino acid substitution F514V with reference to NM_003215. F514V is reported in GenBank CB985022. |
Target Class: | Kinase |
Accession Number: | Refer to CoA for Accession Number |
Target Name: | Tec |
Target Aliases: | TEC, PSCTK4 |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 6 months at -70°C |
Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
Tec, activated
Datasheets
14-801x Datasheet
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