TrkC, active

10 µg of active TrkC. N-terminal GST-tagged and C-terminal 6His-tagged recombinant, human TrkC amino acids 510-end.

Catalog #: 14-922

$399.00$2,989.00


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Biological Information
Background Information:
TrkC is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signaling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.
Target Class:
Kinase
Accession Number:
NM_002530
Target Name:
TrkC
Target Aliases:
TRKC, NTRK3, Trk-C
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
Usage Disclaimer:
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Datasheets

14-922x Datasheet

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