Biological Information | |
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Background Information: | Src family kinases, Src, Fyn, and Yes, are expressed in numerous cell types, including neurons and muscle, and their activities are implicated in multiple signaling pathways. YES kinase is believed to play critical roles in tumor growth, angiogenesis, invasion, and dissemination. YES1 (YES) kinase has been implicated in several human cancers, such as advanced colon cancers and endometrial cancer. YES1 kinase inhibitors may be of therapeutic use in the treatment of human cancer.
GenBank M15990 |
Target Class: | Kinase |
Accession Number: | NM_005433.3 |
Target Name: | Yes |
Target Aliases: | YES1, P61-YES, HsT441, Yes, c-yes, YES, p61-Yes |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 1 year at -70°C |
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