Scientific Posters

Showing 49–60 of 71 results

Scientific Posters Measuring Receptor Dimerization To Create Functional Cell-Based Assays for ~85% of the Interleukin Receptor Family

Ligand-induced receptor dimerization is the first functional step in receptor activation, representing the most proximal, functional read-out for receptor activation.…

Read More
Scientific Posters Development of Novel Cell-based Assays to Detect Neutralizing Antibodies to Therapeutic Biologics

Neutralizing antibodies (NAbs) to biological drugs may cause loss of therapeutic efficacy and in some cases, loss of endogenous protein…

Read More
Scientific Posters A Wide Range of Compound Efficacies Revealed Using PathHunter® Arrestin Assays

DiscoveRx has developed a novel application of our established Enzyme Fragment Complementation (EFC) technology that allows us to monitor protein-protein…

Read More
Scientific Posters ADP Hunter™ Plus: A Rapid, Quantitative HTS Assay for GDP and UDP

There are numerous assays available to measure the activity of enzymes involved in the transfer of a phosphate from ATP…

Read More
Scientific Posters Advances in tools to compare potency, efficacy, safety & quality of follow-on biologics or biosimilars

Regulatory authorities define biosimilars as drugs that are “highly similar” to or “interchangeable” with an approved biologic. The lack of…

Read More
Scientific Posters Application of the PathHunter® Protein Interaction Assay to Receptor Tyrosine Kinases (RTKs): Developing a Non-Antibody One-Step Cell-Based Kinase Activity

Kinase targets have been extensively studied in biochemical assays using purified protein fragments for the kinase and the substrate. However,…

Read More
Scientific Posters Building Better Cell-Based Assays for Interleukins and Their Receptors

Ligand-induced receptor dimerization is an early functional step in receptor activation, representing the most proximal, functional read-out for Interleukin receptors.…

Read More
Scientific Posters Building Robust and Simple Cell-Based Assays for Interleukins and Their Receptors

Ligand-induced receptor dimerization is an early functional step in receptor activation, representing the most proximal, functional readout for Interleukin receptors.…

Read More
Scientific Posters CAR-T Cell Screening in Tumor Spheroids Using Corning Spheroid Microplates

Chimeric antigen receptor (CAR)-T cells, which are engineered to recognize target cell surface antigens expressed on tumor cells, have shown…

Read More
Scientific Posters Cell-Based Assays for G-Protein Independent Signaling Using Arrestin Binding and Endocytosis

GPCR activation results in G-protein dependent events such as second messenger signaling, as well as initiation of a host of…

Read More
Scientific Posters Detection of Cytokine and Growth Factor Receptor Dimerization Using Enzyme Fragment Complementation

Ligand-induced receptor dimerization is the first functional step in receptor activation, representing the most proximal, functional read-out for receptor activation.…

Read More
Scientific Posters Detection of EGFR, HER2, HER3 and HER4 Hetero- and Homodimerization Using EFC-based Cellular Assays

Ligand-induced receptor dimerization is the first functional step in receptor activation, representing the most proximal, functional read-out for receptor activation.…

Read More
Contact