Explore LeadHunter® Drug Discovery Services Panels
On-Target and Off-Target Screening & Profiling
Designed for lead optimization and safety pharmacology profiling, LeadHunter panels can be used to rapidly assess a compound’s on-target activity or off-target liability. In addition, these panels offer functional or binding assays that can be used to validate new targets or tool compounds. With the fastest turnaround times and the largest menu of assays, the LeadHunter Services panels serve as ideal tools to expedite decision making during SAR in Lead Optimization. Assessing the specificity and selectivity of lead compounds early in development using highly relevant and predictive assays allows more informed decisions about compound safety and efficacy, ultimately leading to safer and more effective drugs.
LeadHunter Panels for In Vitro Pharmacology Profiling Services Highlights:
- The largest menu of thoroughly validated human assays for selectivity screening & safety profiling
- Fastest delivery of comprehensive data reports, ensuring timely critical decisions can be made with confidence
- Over 15 years of industry experience, consistently ranked as the highest quality services
Panel
|
Target Class |
Number of Targets |
Applications |
Turnaround Time |
Safety47™ |
GPCR, Kinase, Nuclear Hormone Receptors,
Ion Channels, and Enzymes |
47 |
Safety Profiling |
20 days* |
* Turnaround time is 20 business days from scheduled panel dates
PathHunter® Service Panels
Panel
|
Target Class |
Number of Targets |
Applications |
Turnaround Time |
gpcrMAX™ |
GPCR |
168 |
Selectivity, Specificity, Target Validation |
20 days* |
orphanMAX™ |
Orphan GPCR |
73 |
Ligand Fishing, De-Orphanization Programs |
20 days* |
nhrMAX™ |
Nuclear Hormone Receptor |
19 |
Selectivity, Specificity, Compound Liability |
20 days* |
tkMAX™ |
Tyrosine Kinase |
25 |
Selectivity, Target Validation |
20 days* |
pathMAX |
Pathway Assays |
13 |
Mechanism of Action of Drug Candidates |
20 days* |
* Click here to view the PathHunter Panel Run Schedule. Turnaround time is 20 business days from scheduled panel dates.
KINOMEscan® Service Panels
Panel
|
Target Class |
Number of Targets |
Applications |
Turnaround Time |
scanMAX® |
Kinase |
468 |
Selectivity, Target Validation |
<10 days* |
scanEDGE® |
Kinase |
97 |
Selectivity, Target Validation |
<10 days* |
bromoMAX™ |
Bromodomain |
32 |
Selectivity, Target Validation |
20 days |
bcl2KdMAX |
BCL2 Family Proteins |
5 |
Selectivity, Target Validation |
20 days |
*
Eligible projects are activated on Friday