Flexible Screening & Profiling Options
LeadHunter Discovery Services reduces the time and costs associated with drug discovery. Whether you are interested in full panel screening and profiling, or selecting a subset of assays, we offer the selection and flexibility to support your drug discovery needs.
Overview of PATHscan℠ Panels & Services
Services |
Assays |
Pre-configured Panel |
Customizable? |
Standard Turnaround |
pathELECT |
19 |
No |
Yes |
3 weeks |
pathE/IC50ELECT |
19 |
No |
Yes |
3 weeks |
pathMAX |
13 |
Yes |
No |
4 weeks |
Although standard turnaround times for ELECT assays are 3 weeks, express turnaround times of 10 days can be requested.
PATHscan Assay List
Below is a complete list of available PATHscan assays. The list can be sorted by "Target Gene", "Gene ID", "GeneBank Accession Number", or "Species".
Target Gene ▲ | Common Name | Family | Accession No. |
BCL2-BAX | BCL2 B-cell CLL/lymphoma 2 (Bcl-2) | BCL2 | NM_000633 |
BCL2-BIM | BCL2 B-cell CLL/lymphoma 2 (Bcl-2) | BCL2 | NM_000633 |
BCL2L1-BAX | BCL2-like 1 (Bcl-xL) | BCL2 | NM_138578.1 |
BCL2L1-BIM | BCL2-like 1 (Bcl-xL) | BCL2 | NM_138578.1 |
CDC25A | Cell division cycle 25 homolog A (CDC25A) | Cell Cycle Protein | NM_001789.2 |
FOXO3 | forkhead box O3 (forkhead box O3) | Pathway | NM_001455 |
IκB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA) | Pathway | NM_020529 |
Keap1-NRF2 | nuclear factor (erythroid-derived 2)-like 2 (NFE2L2) | Transcription Factor | NM_006164 |
MCL1-BIM | Myeloid cell leukemia sequence 1 (Mcl-1) | BCL2 | NM_021960 |
NIK | mitogen-activated protein kinase kinase kinase 14 (NIK) | STE | NP_003945.2 |
P53 | P53 (P53) | Nuclear Translocation | NM_000546.2 |
RANK-IκB | Tumor necrosis factor receptor superfamily, member 11a (TNFRSF11A) | Tumor Necrosis Factor Receptor Superfamily | NM_003839.3 |
RELA-IκB | v-rel reticuloendotheliosis viral oncogene homolog A (avian) (RELA) | Transcription factor | NM_021975 |
SREBP2 | Sterol regulatory element binding transcription factor 2 (SREBF2) | Transcription Factor | NM_004599.2 |
TORC1 | CREB regulated transcription coactivator 1 (CRTC1) | Transcription factor | NM_015321.1 |
TORC2 | CREB regulated transcription coactivator 2 (CRTC2) | Transcription factor | NM_181715 |
XBP1 | X-box binding protein 1 (XBP1) | Transcription factor | BC012841 |
β-Catenin | Catenin (cadherin-associated protein), beta 1 (CTNNB1) | Wnt-Frizzled signalling | NM_001904 |