Adenosine receptor A1 (A1)
- Target Class
- GPCR
- Family
- Adenosine
- Official Symbol
- ADORA1
- Species
- Human
- Accession Number
- AY136746
- Alias Names
- RDC7; adenosine A1 receptor; adenosine receptor A1
- Background
The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Adenosine
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
CHO-K1 |
Human |
93-0787C2 |
| cAMP |
CHO-K1 |
Human |
95-0061C2 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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