Bradykinin receptor B2 (B2)
- Target Class
- GPCR
- Family
- Bradykinin
- Official Symbol
- BDKRB2
- Species
- Human
- Accession Number
- NM_000623.3
- Alias Names
- B2 bradykinin receptor; B2R; BK-2; BK-2 receptor; BK2; BKR2; BRB2; bradykinin receptor B2
- Background
This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Bradykinin
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
HEK 293 |
Human |
93-0189C1 |
| β-Arrestin |
CHO-K1 |
Human |
93-0189C2 |
| Internalization |
U2OS |
Human |
93-0725C3 |
| Assay Qualified With |
Assay Measures |
Background |
Species |
Assay Kit |
|
β-Arrestin |
CHO-K1 |
Human |
93-0189Y2-00113 |
| Bradykinin |
β-Arrestin |
CHO-K1 |
Human |
93-0189Y2-00114 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
| |
|
|
|
Available |
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