Bradykinin receptor B2 (B2)

Target Class
GPCR
Family
Bradykinin
Official Symbol
BDKRB2
Species
Human
Accession Number
NM_000623.3
Alias Names
B2 bradykinin receptor; B2R; BK-2; BK-2 receptor; BK2; BKR2; BRB2; bradykinin receptor B2
Background
This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. [provided by RefSeq, Jul 2008]
+ Show More

Solution Portfolio

Related Family Members:

Bradykinin
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin HEK 293 Human 93-0189C1
β-Arrestin CHO-K1 Human 93-0189C2
Internalization U2OS Human 93-0725C3
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0189E2CP0M
β-Arrestin CHO-K1 Human 93-0189E2CP0L
Assay Qualified With Assay Measures Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0189Y2-00113
Bradykinin β-Arrestin CHO-K1 Human 93-0189Y2-00114
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
The DiscoveRx Advantage:
Access your Target with Three Signaling Platforms