Calcitonin receptor-like (Calcitonin receptor-like receptor)

Target Class
Official Symbol
Accession Number
Alias Names
CRLR activity-modifying protein 1; calcitonin receptor-like receptor activity modifying protein 1; calcitonin-receptor-like receptor activity-modifying protein 1; receptor (G protein-coupled) activity modifying protein 1; receptor (calcitonin) activity modifying protein 1; receptor activity modifying protein 1; receptor activity-modifying protein 1
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:


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Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0269C2
cAMP CHO-K1 Human 95-0164C2
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0269E2CP0M
β-Arrestin CHO-K1 Human 93-0269E2CP0L
cAMP CHO-K1 Human 95-0164E2CP2M
cAMP CHO-K1 Human 95-0164E2CP2L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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