Calcitonin receptor-like (Calcitonin receptor-like receptor)

Target Class
Official Symbol
Accession Number
Alias Names
CRLR activity-modifying protein 3; calcitonin receptor-like receptor activity modifying protein 3; calcitonin-receptor-like receptor activity-modifying protein 3; receptor (G protein-coupled) activity modifying protein 3; receptor (calcitonin) activity modifying protein 3; receptor activity modifying protein 3; receptor activity-modifying protein 3; receptor-activity-modifying protein 3
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor. [provided by RefSeq, Jul 2008]
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Related Family Members:


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Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0252C2
cAMP CHO-K1 Human 95-0169C2
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0252E2CP0M
β-Arrestin CHO-K1 Human 93-0252E2CP0L
cAMP CHO-K1 Human 95-0169E2CP2M
cAMP CHO-K1 Human 95-0169E2CP2L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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