Chemokine (C-C motif) receptor 2 (CCR2)
- Target Class
- GPCR
- Family
- Chemokine
- Official Symbol
- CCR2
- Species
- Human
- Accession Number
- NM_001123396
- Alias Names
- C-C chemokine receptor type 2; CC-CKR-2; CCR-2; CCR2A; CCR2B; CD192; CKR2; CKR2A; CKR2B; CMKBR2; MCP-1 receptor; MCP-1-R; chemokine (C-C motif) receptor 2; monocyte chemoattractant protein 1 receptor; monocyte chemotactic protein 1 receptor
- Background
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009]
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Solution Portfolio
Related Family Members:
Chemokine
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Assay Qualified With |
Assay Measures |
Background |
Species |
Assay Kit |
CCL2 |
β-Arrestin |
CHO-K1 |
Human |
93-0192Y2-00062 |
CCL2 |
β-Arrestin |
CHO-K1 |
Human |
93-0192Y2-00061 |
KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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