CCR4 -

Targets

Chemokine (C-C motif) receptor 4 (CCR4)

Target Class

GPCR

Family

Chemokine

Official Symbol

CCR4

Species

Human

Accession Number

AY322539

Alias Names

C-C CKR-4; C-C chemokine receptor type 4; CC-CKR-4; CCR-4; CD194; CKR4; CMKBR4; ChemR13; HGCN:14099; K5-5; chemokine (C-C motif) receptor 4; chemokine (C-C) receptor 4

Background

The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008]

+ Show More

Related Family Members:

Chemokine

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family