Chemokine (C-C motif) receptor 6 (CCR6)
- Target Class
- GPCR
- Family
- Chemokine
- Official Symbol
- CCR6
- Species
- Human
- Accession Number
- AY242126
- Alias Names
- BN-1; C-C CKR-6; C-C chemokine receptor type 6; CC-CKR-6; CCR-6; CD196; CKR-L3; CKRL3; CMKBR6; DCR2; DRY6; G protein-coupled receptor 29; G-protein coupled receptor 29; GPR29; GPRCY4; LARC receptor; STRL22; chemokine (C-C motif) receptor 6; chemokine (C-C) receptor 6; chemokine receptor-like 3; seven-transmembrane receptor, lymphocyte, 22
- Background
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Chemokine
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