Dopamine Receptor D2 (short isoform) (D2S)

Target Class
Official Symbol
Accession Number
Alias Names
D(2) dopamine receptor; D2DR; D2R; dopamine D2 receptor; dopamine receptor D2; dopamine receptor D2 isoform; seven transmembrane helix receptor
This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]
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Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0351C2
cAMP CHO-K1 Human 95-0084C2
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0084E2CP2M
cAMP CHO-K1 Human 95-0084E2CP2L
β-Arrestin CHO-K1 Human 93-0351E2CP0M
β-Arrestin CHO-K1 Human 93-0351E2CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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