Dopamine Receptor D2 (short isoform) (D2S)
- Target Class
- GPCR
- Family
- Dopamine
- Official Symbol
- DRD2S
- Species
- Human
- Accession Number
- NM_016574.3
- Alias Names
- D(2) dopamine receptor; D2DR; D2R; dopamine D2 receptor; dopamine receptor D2; dopamine receptor D2 isoform; seven transmembrane helix receptor
- Background
This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]
+ Show More
Solution Portfolio
Related Family Members:
Dopamine
?
DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
CHO-K1 |
Human |
93-0351C2 |
| cAMP |
CHO-K1 |
Human |
95-0084C2 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
| |
|
|
|
Available |
|
The DiscoveRx Advantage:
Access your Target with Three Signaling Platforms