Sphingosine 1-phosphate receptor 1 (S1P1)
- Target Class
- GPCR
- Family
- Lysophospholipid (S1P)
- Official Symbol
- EDG1
- Species
- Human
- Accession Number
- NM_001400
- Alias Names
- S1PR1; CD363; CHEDG1; D1S3362; ECGF1; EDG-1; EDG1; S1P receptor 1; S1P receptor Edg-1; S1P1; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; sphingosine 1-phosphate receptor 1; sphingosine 1-phosphate receptor EDG1; sphingosine 1-phosphate receptor Edg-1; sphingosine-1-phosphate receptor 1
- Background
The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Lysophospholipid (S1P)
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