Sphingosine 1-phosphate receptor 1 (S1P1)

Target Class
Lysophospholipid (S1P)
Official Symbol
Accession Number
Alias Names
S1PR1; CD363; CHEDG1; D1S3362; ECGF1; EDG-1; EDG1; S1P receptor 1; S1P receptor Edg-1; S1P1; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; sphingosine 1-phosphate receptor 1; sphingosine 1-phosphate receptor EDG1; sphingosine 1-phosphate receptor Edg-1; sphingosine-1-phosphate receptor 1
The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Lysophospholipid (S1P)

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family

Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0207C2
Internalization HEK 293 Human 93-0784C1
cAMP CHO-K1 Human 95-0142C2
Chem-4 Human HTS176C
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0207E2CP4M
β-Arrestin CHO-K1 Human 93-0207E2CP4L
Internalization HEK 293 Human 93-0784E1CP28M
Internalization HEK 293 Human 93-0784E1CP28L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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