Lysophosphatidic acid receptor 2 (LPA2)
- Target Class
- GPCR
- Family
- Lysophospholipid (LPA)
- Official Symbol
- EDG4
- Species
- Human
- Accession Number
- AY322548
- Alias Names
- LPAR2; EDG-4; EDG4; G protein-coupled receptor; LPA receptor 2; LPA receptor EDG4; LPA-2; LPA2; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4; lysophosphatidic acid receptor 2; lysophosphatidic acid receptor EDG4; lysophosphatidic acid receptor Edg-4
- Background
This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Lysophospholipid (LPA)
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
CHO-K1 |
Human |
93-0255C2 |
| Calcium |
CHO-K1 |
Human |
95-1012C2 |
|
Chem-1 |
Human |
HTS207C |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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