Free fatty acid receptor 3 (GPR41)
- Target Class
- GPCR
- Family
- Free Fatty Acid
- Official Symbol
- FFAR3
- Species
- Human
- Accession Number
- NM_005304.3
- Alias Names
- FFA3R; G protein-coupled receptor 41; G-protein coupled receptor 41; GPR41; free fatty acid receptor 3
- Background
Receptor for short chain fatty acids. The activity of this receptor is coupled to the formation of inositol 1,4,5- trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation. Coupled exclusively to the pertussis toxin-sensitive G(i/o)-alpha protein. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.
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Solution Portfolio
Related Family Members:
Free Fatty Acid
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| Assay Readout |
Background |
Species |
Cell Line |
| cAMP |
CHO-K1 |
Human |
95-0136C2 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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|
Available |
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