Free fatty acid receptor 3 (GPR41)
- Target Class
- GPCR
- Family
- Free Fatty Acid
- Official Symbol
- FFAR3
- Species
- Human
- Accession Number
- NM_005304.3
- Alias Names
- FFA3R; G protein-coupled receptor 41; G-protein coupled receptor 41; GPR41; free fatty acid receptor 3
- Background
Receptor for short chain fatty acids. The activity of this receptor is coupled to the formation of inositol 1,4,5- trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation. Coupled exclusively to the pertussis toxin-sensitive G(i/o)-alpha protein. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.
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Solution Portfolio
Related Family Members:
Free Fatty Acid
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
Assay Readout |
Background |
Species |
Cell Line |
cAMP |
CHO-K1 |
Human |
95-0136C2 |
KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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