Formylpeptide receptor-like 1 (FPR2/ALX)
- Target Class
- GPCR
- Family
- Formylpeptide
- Official Symbol
- FPRL1
- Species
- Human
- Accession Number
- AY225226
- Alias Names
- ALXR; FMLP-R-I; FMLP-R-II; FMLP-related receptor I; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; HM63; LXA4 receptor; LXA4R; N-formyl peptide receptor 2; RFP; formyl peptide receptor 2; formyl peptide receptor-like 1; lipoxin A4 receptor (formyl peptide receptor related)
- Background
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
+ Show More
Solution Portfolio
Related Family Members:
Formylpeptide
?
DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
| |
|
|
|
Available |
|
The DiscoveRx Advantage:
Access your Target with Three Signaling Platforms