Galanin receptor 1 (GALR1)
- Target Class
- GPCR
- Family
- Galanin
- Official Symbol
- GALR1
- Species
- Human
- Accession Number
- AY541036
- Alias Names
- GAL1-R; GALNR; GALNR1; GALR-1; galanin receptor 1; galanin receptor type 1
- Background
The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Galanin
?
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| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
CHO-K1 |
Human |
93-0228C2 |
| Internalization |
U2OS |
Human |
93-0781C3 |
| cAMP |
CHO-K1 |
Human |
95-0058C2 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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