Gastric inhibitory polypeptide receptor (GIP)
- Target Class
- GPCR
- Family
- Glucagon
- Official Symbol
- GIPR
- Species
- Human
- Accession Number
- NM_000164
- Alias Names
- GIP-R; PGQTL2; gastric inhibitory polypeptide receptor; glucose-dependent insulinotropic polypeptide receptor
- Background
This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011]
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Solution Portfolio
Related Family Members:
Glucagon
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| cAMP |
CHO-K1 |
Human |
95-0146C2 |
| β-Arrestin |
CHO-K1 |
Human |
93-1095C2 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
| |
|
|
|
Available |
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