G-protein coupled receptor 35 (GPR35)
- Target Class
- GPCR
- Family
- Class A Orphan
- Official Symbol
- GPR35
- Species
- Human
- Accession Number
- NM_005301
- Alias Names
- G protein-coupled receptor 35; G-protein coupled receptor 35; KYNA receptor; kynurenic acid receptor
- Background
Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins.
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Solution Portfolio
Related Family Members:
Class A Orphan
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| Assay Readout |
Background |
Species |
Cell Line |
| cAMP |
CHO-K1 |
Human |
95-0152C2 |
| β-Arrestin |
CHO-K1 |
Human |
93-0942C2 |
| Internalization |
U2OS |
Human |
93-0968C3 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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|
Available |
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