G-protein coupled receptor 85 (GPR85)
- Target Class
- GPCR
- Family
- Class A Orphan
- Official Symbol
- GPR85
- Species
- Human
- Accession Number
- NM_018970
- Alias Names
- G protein-coupled receptor 85; SREB; SREB2; probable G-protein coupled receptor 85; seven transmembrane helix receptor; super conserved receptor expressed in brain 2
- Background
Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins (Matsumoto et al., 2000 [PubMed 10833454]).[supplied by OMIM, Aug 2008]
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Solution Portfolio
Related Family Members:
Class A Orphan
?
DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
CHO-K1 |
Human |
93-0409C2A |
| β-Arrestin |
U2OS |
Human |
93-0409C3 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
| |
|
|
|
Available |
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