G-protein coupled receptor 85 (GPR85)

Target Class
GPCR
Family
Class A Orphan
Official Symbol
GPR85
Species
Human
Accession Number
NM_018970
Alias Names
G protein-coupled receptor 85; SREB; SREB2; probable G-protein coupled receptor 85; seven transmembrane helix receptor; super conserved receptor expressed in brain 2
Background
Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins (Matsumoto et al., 2000 [PubMed 10833454]).[supplied by OMIM, Aug 2008]
+ Show More

Solution Portfolio

Related Family Members:

Class A Orphan
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0409C2A
β-Arrestin U2OS Human 93-0409C3
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0409E2ACP1M
β-Arrestin CHO-K1 Human 93-0409E2ACP1L
β-Arrestin U2OS Human 93-0409E3CP1M
β-Arrestin U2OS Human 93-0409E3CP1L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
The DiscoveRx Advantage:
Access your Target with Three Signaling Platforms