Histamine receptor H2 (H2)
- Target Class
- GPCR
- Family
- Histamine
- Official Symbol
- HRH2
- Species
- Human
- Accession Number
- AY136744
- Alias Names
- H2R; HH2R; gastric receptor 1; gastric receptor I; histamine H2 receptor; histamine receptor H2
- Background
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
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Solution Portfolio
Related Family Members:
Histamine
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
Assay Readout |
Background |
Species |
Cell Line |
β-Arrestin |
CHO-K1 |
Human |
93-0208C2 |
cAMP |
CHO-K1 |
Human |
95-0043C2 |
KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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