5-hydroxytryptamine receptor 2B (5HT2B)

Target Class
Official Symbol
Accession Number
Alias Names
5-HT 2B receptor; 5-HT(2B); 5-HT-2B; 5-HT2B; 5-hydroxytryptamine (serotonin) receptor 2B; 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled; 5-hydroxytryptamine 2B receptor; 5-hydroxytryptamine receptor 2B; 5-hydroxytryptamine receptor 2B variant b; serotonin receptor 2B
This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. [provided by RefSeq, Oct 2011]
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Assay Readout Background Species Cell Line
Calcium HEK 293 Human 95-1024C1
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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