KISS1-derived peptide receptor (kisspeptin)
- Target Class
- GPCR
- Family
- Kisspeptin receptor
- Official Symbol
- KISS1R
- Species
- Human
- Accession Number
- NM_032551
- Alias Names
- AXOR12; G protein-coupled receptor 54; G-protein coupled receptor 54; G-protein coupled receptor OT7T175; GPR54; HOT7T175; KISS1 receptor; hypogonadotropin-1; kiSS-1 receptor; kiSS-1R; kisspeptins receptor; metastin receptor
- Background
The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Kisspeptin receptor
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
C2C12 |
Human |
93-0504C7 |
| β-Arrestin |
U2OS |
Human |
93-0927C3 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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