Choriogonadotropin receptor (LH)
- Target Class
- GPCR
- Family
- Glycoprotein hormone receptor
- Official Symbol
- LHCGR
- Species
- Human
- Accession Number
- NM_000233
- Alias Names
- HHG; LCGR; LGR2; LH/CG-R; LH/CGR; LHR; LHRHR; LSH-R; ULG5; hypergonadotropic hypogonadism; luteinizing hormone/choriogonadotropin receptor; lutropin-choriogonadotropic hormone receptor; lutropin/choriogonadotropin receptor
- Background
This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Glycoprotein hormone receptor
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| cAMP |
CHO-K1 |
Human |
95-0106C2 |
| β-Arrestin |
CHO-K1 |
Human |
93-0957C2 |
| Assay Qualified With |
Assay Measures |
Background |
Species |
Assay Kit |
| Human Luteinizing Hormone |
cAMP |
CHO-K1 |
Human |
95-0106Y2-00138 |
| Human Luteinizing Hormone |
cAMP |
CHO-K1 |
Human |
95-0106Y2-00137 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
| |
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Available |
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