Melanocortin receptor 3 (MC3)
- Target Class
- GPCR
- Family
- Melanocortin
- Official Symbol
- MC3R
- Species
- Human
- Accession Number
- AY227893
- Alias Names
- BMIQ9; MC3; MC3-R; OB20; OQTL; Obesity quantitative trait locus; melanocortin 3 receptor; melanocortin receptor 3
- Background
This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Melanocortin
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| Internalization |
U2OS |
Human |
93-0837C3 |
| cAMP |
CHO-K1 |
Human |
95-0045C2 |
| β-Arrestin |
U2OS |
Human |
93-0984C3 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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