Neuropeptide FF receptor 1 (NPFF1)
- Target Class
- GPCR
- Family
- Neuropeptide FF & AF
- Official Symbol
- NPFFR1
- Species
- Human
- Accession Number
- NM_022146
- Alias Names
- G protein-coupled receptor 147; G-protein coupled receptor 147; GPR147; NPFF1; NPFF1R1; OT7T022; RFamide-related peptide receptor OT7T022; neuropeptide FF 1; neuropeptide FF receptor 1
- Background
Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system.
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Solution Portfolio
Related Family Members:
Neuropeptide FF & AF
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
Assay Readout |
Background |
Species |
Cell Line |
cAMP |
CHO-K1 |
Human |
95-0097C2 |
β-Arrestin |
CHO-K1 |
Human |
93-0944C2 |
KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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