Opioid receptor-like receptor (NOP)
- Target Class
- GPCR
- Family
- Opioid
- Official Symbol
- OPRL1
- Species
- Human
- Accession Number
- AY268428
- Alias Names
- KOR-3; NOCIR; OOR; ORL1; kappa-type 3 opioid receptor; kappa3-related opioid receptor; nociceptin receptor; opiate receptor-like 1; orphanin FQ receptor
- Background
The protein encoded by this gene is a G protein-coupled receptor whose expression can be induced by phytohemagglutinin. The encoded integral membrane protein is a receptor for the 17 aa neuropeptide nociceptin/orphanin FQ. This gene may be involved in the regulation of numerous brain activities, particularly instinctive and emotional behaviors. A promoter for this gene also functions as a promoter for another gene, regulator of G-protein signalling 19 (RGS19), located on the opposite strand. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2011]
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Solution Portfolio
Related Family Members:
Opioid
?
DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
Assay Readout |
Background |
Species |
Cell Line |
cAMP |
CHO-K1 |
Human |
95-0115C2 |
β-Arrestin |
CHO-K1 |
Human |
93-0264C2 |
Internalization |
U2OS |
Human |
93-0904C3 |
KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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