Opioid receptor-like receptor (NOP)

Target Class
Official Symbol
Accession Number
Alias Names
KOR-3; NOCIR; OOR; ORL1; kappa-type 3 opioid receptor; kappa3-related opioid receptor; nociceptin receptor; opiate receptor-like 1; orphanin FQ receptor
The protein encoded by this gene is a G protein-coupled receptor whose expression can be induced by phytohemagglutinin. The encoded integral membrane protein is a receptor for the 17 aa neuropeptide nociceptin/orphanin FQ. This gene may be involved in the regulation of numerous brain activities, particularly instinctive and emotional behaviors. A promoter for this gene also functions as a promoter for another gene, regulator of G-protein signalling 19 (RGS19), located on the opposite strand. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2011]
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Solution Portfolio

Related Family Members:


DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family

Assay Readout Background Species Cell Line
cAMP CHO-K1 Human 95-0115C2
β-Arrestin CHO-K1 Human 93-0264C2
Internalization U2OS Human 93-0904C3
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0115E2CP2M
cAMP CHO-K1 Human 95-0115E2CP2L
β-Arrestin CHO-K1 Human 93-0264E2CP0M
β-Arrestin CHO-K1 Human 93-0264E2CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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