OPRL1 -

Targets

Opioid receptor-like receptor (NOP)

Target Class

GPCR

Family

Opioid

Official Symbol

OPRL1

Species

Human

Accession Number

AY268428

Alias Names

KOR-3; NOCIR; OOR; ORL1; kappa-type 3 opioid receptor; kappa3-related opioid receptor; nociceptin receptor; opiate receptor-like 1; orphanin FQ receptor

Background

The protein encoded by this gene is a G protein-coupled receptor whose expression can be induced by phytohemagglutinin. The encoded integral membrane protein is a receptor for the 17 aa neuropeptide nociceptin/orphanin FQ. This gene may be involved in the regulation of numerous brain activities, particularly instinctive and emotional behaviors. A promoter for this gene also functions as a promoter for another gene, regulator of G-protein signalling 19 (RGS19), located on the opposite strand. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2011]

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Related Family Members:

Opioid

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family