Opioid receptor mu (μ)

Target Class
GPCR
Family
Opioid
Official Symbol
OPRM1
Species
Human
Accession Number
AY521028
Alias Names
LMOR; M-OR-1; MOP; MOR; MOR1; OPRM; hMOP; mu opiate receptor; mu opioid receptor hMOR-1a; mu opioid receptor splice variant hMOR-1S; mu opioid receptor splice variant hMOR-1Y2; mu opioid receptor splice variant hMOR-1Y3; mu opioid receptor splice variant hMOR-1Z; mu opioid receptor splice variant hMOR-1b; mu-type opioid receptor; opioid receptor, mu 1
Background
This gene encodes one of three opioid receptors. The mu opioid receptor is the principal target of endogenous opioid peptides and opioid analgesic agents. Mutations in this gene have been associated with opioid and alcohol addiction and variations in pain sensitivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
+ Show More

Solution Portfolio

Related Family Members:

Opioid
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
cAMP CHO-K1 Human 95-0107C2
β-Arrestin CHO-K1 Human 93-0213C2
Internalization U2OS Human 93-0745C3
β-Arrestin U2OS Human 93-0213C3
β-Arrestin U2OS Human 93-0878C3
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0107E2CP2M
cAMP CHO-K1 Human 95-0107E2CP2L
β-Arrestin CHO-K1 Human 93-0213E2CP0M
β-Arrestin CHO-K1 Human 93-0213E2CP0L
β-Arrestin U2OS Human 93-0213E3CP0M
β-Arrestin U2OS Human 93-0213E3CP0L
Internalization U2OS Human 93-0745E3CP5M
Internalization U2OS Human 93-0745E3CP5L
β-Arrestin U2OS Human 93-0878E3CP5M
β-Arrestin U2OS Human 93-0878E3CP5L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
The DiscoveRx Advantage:
Access your Target with Three Signaling Platforms