Purinergic receptor P2Y, G-protein coupled, 1 (P2RY1)
- Target Class
- GPCR
- Family
- P2Y
- Official Symbol
- P2RY1
- Species
- Human
- Accession Number
- NM_002563.2
- Alias Names
- ATP receptor; P2 purinoceptor subtype Y1; P2Y purinoceptor 1; P2Y1; platelet ADP receptor; purinergic receptor P2Y, G-protein coupled, 1
- Background
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
P2Y
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| Assay Readout |
Background |
Species |
Cell Line |
| Calcium |
1321N1 |
Human |
95-1018C6 |
| Internalization |
U2OS |
Human |
93-0967C3 |
| β-Arrestin |
U2OS |
Human |
93-0941C3 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
| |
|
|
|
Available |
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