Purinergic receptor P2Y, G-protein coupled, 12 (P2Y12)
- Target Class
- GPCR
- Family
- P2Y
- Official Symbol
- P2RY12
- Species
- Human
- Accession Number
- AY136754
- Alias Names
- ADP-glucose receptor; ADPG-R; BDPLT8; G-protein coupled receptor SP1999; Gi-coupled ADP receptor HORK3; HORK3; P2T(AC); P2Y purinoceptor 12; P2Y(AC); P2Y(ADP); P2Y(cyc); P2Y12; P2Y12 platelet ADP receptor; SP1999; purinergic receptor P2RY12; purinergic receptor P2Y, G-protein coupled, 12; putative G-protein coupled receptor
- Background
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
P2Y
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| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
CHO-K1 |
Human |
93-0262C2 |
| Internalization |
U2OS |
Human |
93-0952C3 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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