Prostaglandin F receptor (FP) (FP)
- Target Class
- GPCR
- Family
- Prostanoid
- Official Symbol
- PTGFR
- Species
- Human
- Accession Number
- NM_000959.3
- Alias Names
- FP; PGF receptor; PGF2 alpha receptor; PGF2-alpha receptor; prostaglandin F receptor (FP); prostaglandin F2 alpha receptor; prostaglandin F2-alpha receptor; prostaglandin receptor (2-alpha); prostanoid FP receptor
- Background
The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Prostanoid
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
Assay Readout |
Background |
Species |
Cell Line |
Calcium |
CHO-K1 |
Human |
95-1009C2 |
Internalization |
U2OS |
Human |
93-0872C3 |
β-Arrestin |
U2OS |
Human |
93-0936C3 |
KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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